Total oxidant/antioxidant status in jaundiced newborns before and after phototherapy
نویسندگان
چکیده
منابع مشابه
Total oxidant/antioxidant status in jaundiced newborns before and after phototherapy.
OBJECTIVE To assess the effect of phototherapy on serum oxidant and antioxidant status in hyperbilirubinemic full-term newborns. METHOD Thirty-four full-term infants from 3 to 10 days of age exposed to phototherapy were studied. The serum antioxidant status was assessed by measuring the total antioxidant capacity (TAC) and individual antioxidant components: vitamin C, uric acid, albumin, thio...
متن کاملHypocalcemia in jaundiced neonates receiving phototherapy
OBJECTIVE To determine the frequency of hypocalcemia in term neonates with jaundice receiving phototherapy. METHODS This was a cross sectional study conducted at Neonatal intensive care unit, National Institute of Child Health, Karachi from 1st January 2014 to 30th December 2014. A total of 123 term neonates with jaundice of either gender managed by phototherapy were enrolled in the study. Ge...
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Background: Bilirubin binds to cell membrane phospholipids, including N-methyl D-aspartate receptor, and causes excessive activation that can lead to neurotoxic effects. Since magnesium is an important inhibitor of this receptor, a comparison can be made between the physiological effects of magnesium and the neurological effects of bilirubin. This study aimed to compare changes in serum magnesi...
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Background: Phototherapy is believed to be a safe method for the management of hyperbilirubinemia. However, there are some controversial issues regarding the genotoxic effects of phototherapy on DNA. The aim of this study was to investigate morphologically both phototherapy-induced DNA double-strand breaks (DSBs) and apoptosis in lymphocytes derived from jaundiced and non-jaundiced neonates. Me...
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Bakground: Phototherapy plays a significant role in the treatment and prevention of hyperbilirubinemia as well as the management of subsequent complications in the newborn. However, this treatment modality may itself result in the development of hypocalcaemia and create serious complications including convulsion and related conditions. Objective: This study was under-taken to investigate photo...
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ژورنال
عنوان ژورنال: Jornal de Pediatria
سال: 2007
ISSN: 0021-7557
DOI: 10.2223/jped.1645